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Displaying results 481 - 490 of 2674 in total
  1. Target

    B2 bradykinin receptor

    go.drugbank.com/bio_entities/BE0003513
    TargetHumans

    Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: B2 bradykinin receptorSynonyms: BK-2 receptor
  2. Target

    Ryanodine receptor 3

    go.drugbank.com/bio_entities/BE0005296
    TransporterTargetHumans

    Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction (PubMed:12354756, PubMed:9395096). May...

    Polypeptides: Ryanodine receptor 3Synonyms: Type 3 ryanodine receptor, Brain-type ryanodine receptor
  3. Target

    5HT3 serotonin receptor

    go.drugbank.com/bio_entities/BE0005582
    TargetHumans

    Polypeptides: 5HT3 serotonin receptor
  4. Target

    B1 bradykinin receptor

    go.drugbank.com/bio_entities/BE0005831
    TargetHumans

    This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation

    Polypeptides: B1 bradykinin receptorSynonyms: BK-1 receptor
  5. Target

    Melanocortin receptor 5

    go.drugbank.com/bio_entities/BE0009684
    TargetHumans

    Order of potency of natural melanocortins in receptor activation is alpha-MSH > ACTH > beta-MSH > gamma-MSH (PubMed:8396929). … G protein-coupled receptor for melanocyte-stimulating hormones (alpha- beta- and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8396929).

    Polypeptides: Melanocortin receptor 5Function: corticotropin receptor activity
  6. Target

    Thyroid hormone receptor

    go.drugbank.com/bio_entities/BE0009811
    TargetHumans and other mammals

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine … Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor alpha, Thyroid hormone receptor betaSynonyms: Nuclear receptor subfamily 1 group A member 1, Nuclear receptor subfamily 1 group A member 2
  7. Target

    Olfactory receptor 1D2

    go.drugbank.com/bio_entities/BE0013079
    TargetHumans

    Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro.

    Polypeptides: Olfactory receptor 1D2Synonyms: Olfactory receptor 17-4, Olfactory receptor OR17-6
  8. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. … May also be a receptor for Leydig insulin-like peptide (INSL3)

    Polypeptides: Relaxin receptor 2Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 8, G protein-coupled receptor 106
  9. Drug

    Testosterone enanthate

    go.drugbank.com/drugs/DB13944
    ApprovedInvestigational

    As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'

  10. Drug

    Calcium Phosphate

    go.drugbank.com/drugs/DB11348
    ApprovedInvestigational

    Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] [L851].