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Displaying results 481 - 490 of 10000 in total
  1. Drug

    Ilginatinib

    go.drugbank.com/drugs/DB12784
    Investigational

    NS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.

    Synonyms: (S)-N-(1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N'-(PYRAZIN-2-YL)PYRIDINE-2,6-DIAMINE, 2,6-PYRIDINEDIAMINE, N2-((1S)-1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N6-2-PYRAZINYL-
  2. Drug

    Gunagratinib

    go.drugbank.com/drugs/DB18191
    Experimental

    Synonyms: (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamide, 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    2-ETHOXYETHYL (2S,3S)-4-((S)-2-BENZYL-3-OXO-4-((3AR,8R,8AS)-2-OXO-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2-D]OXAZOL-8-YL)-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE

    go.drugbank.com/drugs/DB04623
    Experimental

    Synonyms: 2-ETHOXYETHYL (2S,3S)-4-((S)-2-BENZYL-3-OXO-4-((3AR,8R,8AS)-2-OXO-3,3A,8,8A-TETRAHYDRO-2H-INDENO[1,2-D]OXAZOL-8-YL)-2,3-DIHYDRO-1H-PYRROL-2-YL)-3-HYDROXY-1-PHENYLBUTAN-2-YLCARBAMATE
  4. Drug

    Leupeptin

    go.drugbank.com/drugs/DB16961
    Experimental

    Synonyms: L-leucinamide, n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (s)-, L-leucinamide, n-acetyl-l-leucyl-n-((1s)-4-((aminoiminomethyl)amino)-1-formylbutyl)-
  5. Drug

    Elsubrutinib

    go.drugbank.com/drugs/DB18850
    Investigational

    Elsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants

    Synonyms: (s)-4-(1-acryloylpiperidin-3-yl)-1h-indole-7-carboxamide, 1h-indole-7-carboxamide, 4-((3s)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl)-
  6. Drug

    Elapegademase

    go.drugbank.com/drugs/DB14712
    Approved

    Elapegademase is a PEGylated recombinant adenosine deaminase. … It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl

    Synonyms: (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED, -METHOXYPOLY(O
  7. Drug

    4-methylthio-2-oxobutanoic acid

    go.drugbank.com/drugs/DB02238
    Experimental

    Synonyms: S-Methyl-alpha-ketobutyric acid, 2-Keto-4-methylthiobutyric acid
  8. Drug

    SY-5609

    go.drugbank.com/drugs/DB17099
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (S)-7-(dimethylphosphoryl)-3-(2-((6,6-dimethylpiperidin-3-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)-1H-indole-6-carbonitrile, SY 5609
  9. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274088] It was later approved in Europe in January 2025 and in Canada in March 2025. … Sipavibart is a recombinant human IgG1 monoclonal antibody that is long-acting.

    Synonyms: Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody, 1-chain), disulf
  10. Drug

    Methylthioinosine

    go.drugbank.com/drugs/DB02896
    Experimental

    An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-S-methyl-6-thioinosine, 6-methyl-9-ribofuranosylpurine-6-thiol