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Cinchocaine
go.drugbank.com/drugs/DB00527ApprovedVet approvedA local anesthetic of the amide type now generally used for surface anesthesia. … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Mixtures: Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5%, ULTRAPROCT %0,09+%0,09+%0,5 MERHEM, 10 GCategories: Heterocyclic Compounds, 2-RingDG041
go.drugbank.com/drugs/DB05027ExperimentalEP3 is a target that associates with increased risk of various vascular diseases. … DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.
KW-7158
go.drugbank.com/drugs/DB05498ExperimentalKW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity … The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion
Categories: Heterocyclic Compounds, 2-RingCyclopenthiazide
go.drugbank.com/drugs/DB13532ApprovedIt is a positive allosteric modulator at AMPA-A receptors [T28]. … Cyclopenthiazide is a thiazide diuretic with antihypertensive properties.
Categories: Heterocyclic Compounds, 2-RingDovitinib
go.drugbank.com/drugs/DB05928InvestigationalChiron currently has three ongoing Phase I clinical trials for dovitinib. … Dovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 InducersBI 2536
go.drugbank.com/drugs/DB16107InvestigationalBI 2536 is under investigation in clinical trial NCT00376623 (Efficacy and Safety of BI 2536 in Advanced or Metastatic Non Small Cell Lung Cancer).
Categories: Heterocyclic Compounds, 2-RingNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
go.drugbank.com/drugs/DB14427ApprovedInvestigationalNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Mixtures: MENVEO®, MENVEO®Synonyms: Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigenNeuropeptide Y
go.drugbank.com/drugs/DB11788ApprovedInvestigationalWithdrawnNeuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus.
Categories: Neuropeptide Y, drug effectsSynonyms: Neuropeptide YNicotinamide riboside
go.drugbank.com/drugs/DB14933ApprovedInvestigationalWithdrawnNicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis).
Categories: Heterocyclic Compounds, 1-RingTrodusquemine
go.drugbank.com/drugs/DB06333InvestigationalTrodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B.