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Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
BB 21217
go.drugbank.com/drugs/DB17373InvestigationalBB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel] (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP … ) for memory-like T cells.
Pipequaline
go.drugbank.com/drugs/DB13991ExperimentalPipequaline has a similar pharmacological profile to the reported for the benzodiazepines. … Due to these differences, this drug is classified as a nonbenzodiazepine anxiolytic.
AEG35156
go.drugbank.com/drugs/DB06184InvestigationalXIAP interferes with both the intrinsic and extrinsic program-death signaling pathways, which may render tumor cells resistant to apoptosis. … This agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis.
Tyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalAn important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only nonpsychoactive peripheral sympathomimetic effects. … Tyramine acts by inducing the release of catecholamine.
Iprindole
go.drugbank.com/drugs/DB13496ExperimentalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeQuingestanol
go.drugbank.com/drugs/DB13685ExperimentalCategories: Sex Hormones and Modulators of the Genital SystemHydroxyprogesterone
go.drugbank.com/drugs/DB14570InvestigationalCategories: Sex Hormones and Modulators of the Genital SystemAdlinacogene civaparvovec
go.drugbank.com/drugs/DB16788InvestigationalIt uses proprietary zinc finger nuclease (ZFN) genome editing to insert into the DNA of liver cells a copy of the F9 gene, which controls the production of Factor IX. … [L46711] Developed by Sangamo Therapeutics Inc., it is being investigated for the treatment of hemophilia B.[L46706]
Indopan
go.drugbank.com/drugs/DB01446ExperimentalIllicitIt was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United states. … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar.