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Displaying results 4931 - 4940 of 10000 in total
  1. Drug

    2-Methoxyestradiol

    go.drugbank.com/drugs/DB02342
    Investigational

    2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.

  2. Drug

    Thioredoxin

    go.drugbank.com/drugs/DB11298
    Approved

    Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products. … It plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin.

  3. Drug

    Isoxsuprine

    go.drugbank.com/drugs/DB08941
    ApprovedWithdrawn

    Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

  4. Drug

    Vintafolide

    go.drugbank.com/drugs/DB05168
    Investigational

    Vintafolide is a folate-targeted chemotherapeutic conjugate (folate vitamin + vinca alkaloid) in clinical stage development as a treatment for folate-receptor positive cancers.

  5. Drug

    Fibrinolysin

    go.drugbank.com/drugs/DB05254
    Investigational

    The ointment is marketed by Pfizer under the brand name Fibrolan in a variety of countries (e.g. Switzerland). It is currently not approved in the USA. … Fibrinolysin is used as a local healing ointment when combined together with the enzyme deoxyribonuclease I (extracted from bovine pancreas).

  6. Drug

    Pucotenlimab

    go.drugbank.com/drugs/DB17552
    ApprovedInvestigational

    [A257296] It is being investigated in other cancers. … Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours.

  7. Drug

    Caldaret

    go.drugbank.com/drugs/DB06231
    Investigational

  8. Drug

    Bird pepper

    go.drugbank.com/drugs/DB14262
    Approved

    Bird pepper is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  9. Drug

    Milk thistle

    go.drugbank.com/drugs/DB14375
    ApprovedInvestigational

    Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  10. Drug

    Hydroquinidine

    go.drugbank.com/drugs/DB15300
    Investigational

    Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class Ia