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N,N,N-trimethylglycinium
go.drugbank.com/drugs/DB04455InvestigationalAs a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. … A naturally occurring compound that has been of interest for its role in osmoregulation.
Amsilarotene
go.drugbank.com/drugs/DB21085InvestigationalAmsilarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Amsilarotene is a arotinoid derivative. … Amsilarotene has a monoisotopic molecular weight of 385.15 Da.
Macelignan
go.drugbank.com/drugs/DB14129InvestigationalMacelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsGo-6976
go.drugbank.com/drugs/DB17029ExperimentalAn inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Synonyms: 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-N-oleoyldopamine
go.drugbank.com/drugs/DB17036ExperimentalN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.[A253042]
SRT-1720
go.drugbank.com/drugs/DB17057ExperimentalSRT-1720 is an activator of NAD(+)-dependent histone deacetylase SIRT1.[A253147]
Edralbrutinib
go.drugbank.com/drugs/DB18095InvestigationalEdralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.
VCN-01
go.drugbank.com/drugs/DB18193InvestigationalVCN-01 is an investigational, genetically modified human adenovirus encoding human PH20.
Acediasulfone
go.drugbank.com/drugs/DB08926ExperimentalAcediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Tasimelteon
go.drugbank.com/drugs/DB09071ApprovedInvestigationalIn blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates