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Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
Barbexaclone
go.drugbank.com/drugs/DB09001ExperimentalThere has been a case of barbexaclone abuse due to the amphetamine like properties of propylhexedrine, although the comparative abuse potential is much lower than amphetamine. … of phenobarbital.
Tenamfetamine
go.drugbank.com/drugs/DB01509IllicitInvestigationalAn amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. … It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeRTA 744
go.drugbank.com/drugs/DB05920InvestigationalAnthracyclines are one of the most broadly used and effective classes of cancer therapies; however, they are not used to treat brain cancers because current therapies do not cross the blood-brain barrier … RTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers.
Banoxantrone
go.drugbank.com/drugs/DB04975InvestigationalIt has been shown to work synergistically with fractionated radiation to significantly delay growth of tumours compared to administration of either banoxantrone or radiation alone. … Banoxantrone was also efficacious in tumour models when administered in combination with either cisplatin or chemoradiation. [A3115]
Cloperastine
go.drugbank.com/drugs/DB09002InvestigationalCloperastine is a cough suppressant that acts on the central nervous system.
Mixtures: Facol Classic OneVabicaserin
go.drugbank.com/drugs/DB12071InvestigationalVabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTroleandomycin
go.drugbank.com/drugs/DB13179ApprovedA macrolide antibiotic that is similar to erythromycin.
Aconiazide
go.drugbank.com/drugs/DB17731ExperimentalSynonyms: Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazideCategories: Drugs for Treatment of TuberculosisCYT006-AngQb
go.drugbank.com/drugs/DB05739InvestigationalIt is a unique treatment modality that aims to address the issue of patient compliance by offering convenient dosing schedules due to the long-lasting effect induced by vaccination. … CYT006-AngQb is a therapeutic vaccine in development for treatment of hypertension.