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Displaying results 4931 - 4940 of 7058 in total
  1. Drug

    Ivacaftor

    go.drugbank.com/drugs/DB08820
    ApprovedInvestigational

    [L6841] Ivacaftor is administered as a monotherapy and also administered in combination with other drugs for the management of CF. … Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals.

    Synonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
  2. Drug

    Tinzaparin

    go.drugbank.com/drugs/DB06822
    ApprovedInvestigational

    Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin III (ATIII). This complex greatly accelerates the inhibition of factor Xa. … It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons.

    Products: .-11700 Anti-XA Iu/ml, INNOHEP 20.000 ANTI XA 0.5
  3. Drug

    Melphalan

    go.drugbank.com/drugs/DB01042
    ApprovedInvestigational

    Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent.

    Synonyms: 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine, p-Di-(2-chloroethyl)amino-L-phenylalanine
  4. Drug

    Doravirine

    go.drugbank.com/drugs/DB12301
    ApprovedInvestigational

    [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg).

  5. Drug

    Oblimersen

    go.drugbank.com/drugs/DB13811
    Investigational

    Categories: DNA, Antisense, Compounds used in a research, industrial, or household setting
  6. Drug

    OSU-6162

    go.drugbank.com/drugs/DB19178
    Investigational

    OSU-6162 is under investigation in clinical trial NCT05641623 (OSU6162 as Add-on in Ssri/snri-resistant Depression).

    Categories: Dopamine D2 Receptor Antagonists
  7. Drug

    Genistein

    go.drugbank.com/drugs/DB01645
    Investigational

    It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. … Further, genistein is a phytoestrogen which has selective estrogen receptor modulator properties.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Idarubicin

    go.drugbank.com/drugs/DB01177
    ApprovedInvestigational

    An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: IDARUBICINA MYLAN GENERICS
  9. Drug

    Prajmaline

    go.drugbank.com/drugs/DB13555
    Experimental

    Categories: Antiarrhythmics, Class Ia
  10. Drug

    Raclopride

    go.drugbank.com/drugs/DB12518
    Investigational

    Raclopride has been used in trials studying Parkinson Disease.

    Categories: Dopamine D2 Receptor Antagonists