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Nickel sulfate
go.drugbank.com/drugs/DB14180ApprovedNickel sulfate is used in allergenic testing.
Synonyms: nickel(II) sulfateMixtures: Multivitamins and Minerals Tablets, Milltrium Senior Vitamin and Mineral SupplementBavituximab
go.drugbank.com/drugs/DB05136InvestigationalIt binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4. … Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections.
Categories: Amino Acids, Peptides, and ProteinsLigelizumab
go.drugbank.com/drugs/DB11856Investigationala greater affinity for free serum IgE and an altered sensitivity to IgE conformation. … While the precise pathogenesis of CSU is not entirely clear, autoantibodies against IgE receptors, and sometimes against IgE itself, are thought to exist in 30-40% of patients,[A242362,A242367] and the
Categories: Amino Acids, Peptides, and ProteinsBenmoxin
go.drugbank.com/drugs/DB09246ApprovedWithdrawnBenmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was first synthesized in 1967 and rapidly used in Europe as an antidepressant. … However, this agent is no longer marketed.
MK-0752
go.drugbank.com/drugs/DB12852InvestigationalMk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer).
Categories: Gamma Secretase Inhibitors and ModulatorsTaurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalTaurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. … It is also being investigated for its role in inflammation and cancer therapy.
Categories: Bile Acids and Salts, Compounds used in a research, industrial, or household settingRimtuzalcap
go.drugbank.com/drugs/DB16733InvestigationalRimtuzalcap is a novel modulator of small-conductance calcium-activated potassium channels that is under investigation for the treatment of essential tremor.[L38414]
Synonyms: N-(4,4-difluorocyclohexyl)-2-(3-methyl-1H-pyrazol-1-yl)-6-morpholinopyrimidin-4-amineATN-161
go.drugbank.com/drugs/DB05491InvestigationalSince the expression of alpha(5)beta(1) integrin by cancer cells and the role of this molecule in tumor angiogenesis is similar across a range of different cancers, the therapeutic benefit of ATN-161 is … It inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis.
Categories: Amino Acids, Peptides, and ProteinsMetergoline
go.drugbank.com/drugs/DB13520ApprovedMetergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. … Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors.
Categories: Ergot Alkaloids and Derivatives, Genito Urinary System and Sex HormonesOlmutinib
go.drugbank.com/drugs/DB13164InvestigationalIt is available under the brand name Olita made by Hanmi Pharmaceuticals [A19196]. Olmutinib was developed by Hanmi Pharmaceuticals and Boehringer Ingelheim. … Olmutinib is an orally active epidermal growth factor receptor inhibitor used in the treatment of T790M mutation positive non-small cell lung cancer.
Categories: Antineoplastic and Immunomodulating Agents