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Dapoxetine
go.drugbank.com/drugs/DB04884InvestigationalIn October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions. … In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.
Categories: Genito Urinary System and Sex HormonesProducts: Priligy Tablet 30mg, Priligy Tablet 60mg(1R,2S)-2-Phenylcyclopropanaminium
go.drugbank.com/drugs/DB02665Experimental(From AMA Drug Evaluations Annual, 1994, p311) … A propylamine formed from the cyclization of the side chain of amphetamine.
Choriogonadotropin alfa
go.drugbank.com/drugs/DB00097ApprovedInvestigationalRecombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN … -13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit).
Categories: Gonadotropins and Antigonadotropins, Genito Urinary System and Sex HormonesLurbinectedin
go.drugbank.com/drugs/DB12674ApprovedInvestigational[L14336] This accelerated approval is based on the rate and duration of therapeutic response observed in ongoing clinical trials and is contingent on the verification of these results in confirmatory trials … Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,[A214322] and
Categories: Antineoplastic and Immunomodulating AgentsAP1081
go.drugbank.com/drugs/DB05233ExperimentalA transdermal gel containing ethinyl estradiol and norelgestromin being investigated by Antares Pharma for use as a female contraceptive.
Fasinumab
go.drugbank.com/drugs/DB12157InvestigationalNSAIDs and/or opioids) in this patient population.[A241165] NGF was first discovered in the 1950s[A241180] and was the first neurotrophic factor to be identified and biochemically characterized. … It is currently under investigation for the treatment osteoarthritic pain[A241045] and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy (i.e
Categories: Amino Acids, Peptides, and ProteinsNeovastat
go.drugbank.com/drugs/DB05387InvestigationalIt is currently in international Phase III trials for renal cell carcinoma and non-small-cell lung cancer. … Neovastat is a naturally occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of action that provide broad therapeutic potential for a number of diseases
Hydrogen fluoride
go.drugbank.com/drugs/DB11072ApprovedInvestigationalIt is also used as etchant, cleaning agent, and a reagent to dissolve oxides and silicates.
Mixtures: Perfect Choice 0.717% Root and Dentin DesensTecadenoson
go.drugbank.com/drugs/DB04954InvestigationalIt is being developed by CV Therapeutics, Inc.
Categories: Nucleic Acids, Nucleotides, and NucleosidesPAC-113
go.drugbank.com/drugs/DB05756InvestigationalPAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. … PAC-113 is targeting oral Candida infections in immunocompromised patients and patients with salivary dysfunction.