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Displaying results 4971 - 4980 of 9322 in total
  1. Drug

    WVE-003

    go.drugbank.com/drugs/DB17870
    Investigational

    WVE-003 is an allele-selective antisense oligonucleotide that works to selectively reduce the toxic mutant huntingtin (mHTT) protein.[L46787]

  2. Drug

    Benperidol

    go.drugbank.com/drugs/DB12867
    ApprovedWithdrawn

    Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

  3. Drug

    ORE-1001

    go.drugbank.com/drugs/DB12271
    Investigational

    ORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.

  4. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    Exosomes from MSCs carry cytokines and growth factors, like TGFB1, IL-6, IL-10, and hepatocyte growth factor (HGF); all are shown to be immunomodulatory. … Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication.

  5. Drug

    Olendalizumab

    go.drugbank.com/drugs/DB14834
    Investigational

    Olendalizumab is under investigation in clinical trial NCT01883544 (Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALXN1007 in Healthy Male and Female Subjects).

  6. Drug

    Obicetrapib

    go.drugbank.com/drugs/DB14890
    Investigational

    Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).

  7. Drug

    EDI-200

    go.drugbank.com/drugs/DB18188
    Investigational

    EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.

  8. Drug

    HKI-357

    go.drugbank.com/drugs/DB13002
    Investigational

    Hki 357 is under investigation in clinical trial NCT00550381 (Study Evaluating the Safety, Tolerability, and Pharmacokinetics (PK) of HKI-357 Administered Orally to Healthy Subjects).

  9. Drug

    Ex vivo expanded autologous human corneal epithelial cells containing stem cells

    go.drugbank.com/drugs/DB18660
    ApprovedWithdrawn

    Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.[L48375]

  10. Drug

    inBreath airway transplant system

    go.drugbank.com/drugs/DB18692
    Experimental

    inBreath airway transplant system composes of a scaffold seeded with autologous bone marrow cells and incubated in the bioreactor for two days prior to implant.