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Bifemelane

Molybdenum cofactor

Absence of molybdenum cofactor leads to accumulation of toxic levels of sulphite and neurological damage usually leading to death within months of birth, due to the lack of active sulfite oxidase.

3-Methylfentanyl

3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be between 400-6000

AGT-182

AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.

TAK-611

First developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.

Desoxyribonuclease

The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].

Befunolol

Befunolol is a beta blocker introduced in 1983 by Kakenyaku Kakko. It is currently in experimental status, and is being tested for the management of open angle glaucoma.

MaxAdFVIII

First developed by GenStar, it is being investigated for the treatment of hemophilia.

BOS172722

The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects.

Fluspirilene

A long-acting injectable antipsychotic agent used for chronic schizophrenia.