Fluspirilene

DB04842ApprovedWithdrawnSmall molecule

Fluspirilene is an antipsychotic agent used in the treatment of schizophrenia.

Chemical structure of Fluspirilene
Mechanism
Curator reviewed
Primary indication
Used for the treatment of schizophrenia.Curator reviewed · 3 structured indications
Formula / weight
C29H31F2N3O · 475.5727 g/mol (avg)
First approval
Canada, 1977
Code names
Lopac-F-100 · MCN-JR-6218 · R-6218

Resolves to

Compound
UNIIC5QA4GLR9MCAS1841-19-6ChEMBLCHEMBL46516ChEBI93369PubChem3396KEGGD02629
Clinical / RWD
RxNorm4507ATCN05AG01PharmGKBPA162565878
Structure
InChIKeyQOYHHIBFXOOADH-UHFFFAOYSA-NSMILESFC1=CC=C(C=C1)C(CCCN1CCC2(CC1)N(CNC2=O)C1=CC=CC=C1)C1=CC=C(F)C=C1
Targets
P14416DRD2P28223HTR2AQ06432CACNG1

What you can answer from here — as of October 01, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,559Drug interactionsStructured to mechanism, not free text
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3Clinical trialsPhase, status and sponsor resolved per trial
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3Structured indicationsCondition, population, route and combination as fields, not prose
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4ContraindicationsEach with its own population and attribute set
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7Marketed productsAcross 2 countries and 1 labeller
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1ATC codeIncluding every combination product, plus 31 drug categories
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13+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Fluspirilene, and which of those have an active Phase 3 trial?

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