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Displaying results 41 - 50 of 8547 in total
  1. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate.

    Mixtures: Luna Vitamin and Mineral Bar for Women, D Pantothenic 500mg With 100mg CProducts: Calpan Tab 100mg, Pantothenic Acid 100mg
  2. Drug

    Abemaciclib

    go.drugbank.com/drugs/DB12001
    ApprovedInvestigational

    Abemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor, and glioblastoma. … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].

    Products: VERZENIO FILM-COATED TABLET 100MG, Yulareb 100mg film-coated tablets
  3. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Opiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae). … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

    Mixtures: ACETAMINOFEN 500MG / CODEINA 15MG, Acetaminophen 300mg, Caffeine & CodeineProducts: Codeine Contin 100mg Controlled Release Tab, Paveral Liq 10mg/ml
  4. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912]. … Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative.

    Mixtures: Triveen-PRx RNF, Folivane-PRx DHAProducts: Selax Cap 100mg, Colace Cap 100mg
  5. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane.

    Synonyms: -HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3Products: PACLITAXEL 100MG, TARCKOTAXEL® 100MG
  6. Drug

    Diethylstilbestrol

    go.drugbank.com/drugs/DB00255
    ApprovedWithdrawn

    It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.

    Synonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexeneProducts: Honvol Tablets 100mg, Stilbestrol 1.0mg Tablet
  7. Drug

    Thioridazine

    go.drugbank.com/drugs/DB00679
    ApprovedWithdrawn

    It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. … Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.

    Products: Mellaril Tab 100mg, Novo-ridazine 100mg
  8. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. … It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.

    Synonyms: 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridineMixtures: Bal-Care DHA, Vena-Bal DHA
  9. Drug

    Zidovudine

    go.drugbank.com/drugs/DB00495
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.

    Mixtures: COMBIVIR 150MG/300MG, COMBIVIR 150MG/300MGProducts: Novo-azt Cap 100mg, RETROVIR CAPSULAS 100MG
  10. Drug

    Deferiprone

    go.drugbank.com/drugs/DB08826
    ApprovedInvestigational

    As a result, erythropoiesis, the production of new red blood cells, is impaired. FDA approved on October 14, 2011. … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs.

    Products: FERRIPROX 100MG/ML ORAL SOLUTION, Ferriprox Oral Solution 100mg/ml