Pyridoxine is a vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy. Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods.
- Mechanism
- Curator reviewed
Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).
- Primary indication
- Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of DB00951-induced peripheral neuropathy.Curator reviewed · 56 structured indications
- Formula / weight
- C8H11NO3 · 169.1778 g/mol (avg)
- First approval
- Canada, 1996 · United States, 1972
- Also known as
- Pyridoxol · Vitamin B 6 · Vitamin B6 · VitaminB6
- Brand names
Resolves to
LXNHXLLTXMVWPM-UHFFFAOYSA-NSMILESCC1=C(O)C(CO)=C(CO)C=N1What you can answer from here — as of September 23, 2026
Which drugs share a target with Pyridoxine, and which of those have an active Phase 3 trial?
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