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Ixabepilone
go.drugbank.com/drugs/DB04845ApprovedInvestigationalIxabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. … It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: IXEMPRA FOR INJECTION 15 MG, IXEMPRA (FOR INJECTION 15 MG)Palonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalAs of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Solution for Injection 50mcg/ml, ALOXI Solution for Injection 50mcg/mlCeftobiprole medocaril
go.drugbank.com/drugs/DB14733Approvedfor skin and skin structure infections and bacteremia in April 2024. … The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungImiglucerase
go.drugbank.com/drugs/DB00053ApprovedInvestigationalHuman Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human ...
Products: (Imiglucerase) 400U Powder for solution for injectionTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigationalTranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Products: Mar-tranexamic Acid, MEDSAMIC SOLUTION FOR INJECTION 100MG/MLGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Granisetron Kabi concentrate for solution for infusion 1mg/ml, KYTRIL FOR INFUSION 1MG/MLRomiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalEach subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl. … Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor.
Categories: Thrombopoietin Receptor Agonist, Thrombopoietin Receptor AgonistsProducts: ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vialHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalInfection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus.
Categories: Antiinfectives for Systemic UseProducts: UMAN BIG, /ml Pulver und Lösungsmittel zur Herstellung einer InfusionslösungBismuth subcitrate potassium
go.drugbank.com/drugs/DB09275ApprovedInvestigationalA bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Products: KREVAL MAX 22.5 MG/5 ML ŞURUP, 100 MLRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalRopivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V, ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V