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Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes.
PYM50018
go.drugbank.com/drugs/DB05126ExperimentalIt is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). … In pre-clinical models, PYM50018 has been observed to protect against neuronal damage, increase neurite outgrowth, reverse oxidative damage and reverse neuronal apoptosis in vitro.
TTP889
go.drugbank.com/drugs/DB05131InvestigationalTTP889, an orally bioavailable selective inhibitor of the intrinsic coagulation pathway, is being developed as an anticoagulant for the treatment of thromboembolic disorders. … TTP889 has proven to be effective in preventing clot formation in several animal models of human disease, without any signs of the bleeding associated with traditional anticoagulants.
AZD-4877
go.drugbank.com/drugs/DB11671InvestigationalAZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
Rapastinel
go.drugbank.com/drugs/DB11801InvestigationalRapastinel has been used in trials studying the treatment of Depressive Disorder, Major and Obsessive-Compulsive Disorder (OCD).
Ruboxistaurin
go.drugbank.com/drugs/DB11829InvestigationalRuboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
Lucitanib
go.drugbank.com/drugs/DB11845InvestigationalLucitanib has been used in trials studying the treatment of ER+, MBC, SCLC, HER2+, and NSCLC, among others.
Sivelestat
go.drugbank.com/drugs/DB12863InvestigationalSivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Racotumomab
go.drugbank.com/drugs/DB13045InvestigationalRacotumomab has been used in trials studying the treatment of Glioma, Wilm's Tumor, Neuroblastoma, Retinoblastoma, and Ewing's Sarcoma.
2,4-thiazolidinedione
go.drugbank.com/drugs/DB11898InvestigationalThiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.