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Displaying results 5031 - 5040 of 9128 in total
  1. Drug

    PI-103

    go.drugbank.com/drugs/DB17046
    Experimental

    PI-103 is an inhibitor of p110α of class I PI3K.[A253092]

  2. Drug

    SRT-1720

    go.drugbank.com/drugs/DB17057
    Experimental

    SRT-1720 is an activator of NAD(+)-dependent histone deacetylase SIRT1.[A253147]

  3. Drug

    Edralbrutinib

    go.drugbank.com/drugs/DB18095
    Investigational

    Edralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.

  4. Drug

    VCN-01

    go.drugbank.com/drugs/DB18193
    Investigational

    VCN-01 is an investigational, genetically modified human adenovirus encoding human PH20.

  5. Drug

    Acediasulfone

    go.drugbank.com/drugs/DB08926
    Experimental

    Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.

  6. Drug

    DNB-001

    go.drugbank.com/drugs/DB05757
    Investigational

    In preclinical animal models, DNB-001 has demonstrated potent IOP- lowering effects as well as neuroprotective effects on the optic nerve. … DNB-001 is a first-in-class oral therapy with dual mechanism of action, which is initially being developed for the treatment of glaucoma.

  7. Drug

    Chloropyramine

    go.drugbank.com/drugs/DB08800
    Investigational

    Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions.

  8. Drug

    Romlusevimab

    go.drugbank.com/drugs/DB16494
    Investigational

    Romlusevimab (BRII-198) was under investigation in clinical trials (NCT04479644 and NCT04691180) to treat COVID-19, focusing on its safety, tolerability, and pharmacokinetics.

  9. Drug

    Gam-COVID-Vac

    go.drugbank.com/drugs/DB15848
    Investigational

    The vaccine is offered in both a frozen (Gam-COVID-Vac) and freeze-dried formulation (lyophilizate; Gam-COVID-Vac Lyo). … Preliminary results suggested that all participants developed antibodies to the SARS-CoV-2 glycoproteins with a good safety profile in both trials.

    Synonyms: Gam-COVID-Vac Lyo
  10. Drug

    Lemzoparlimab

    go.drugbank.com/drugs/DB17572
    Investigational

    Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Partic...