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Displaying results 5041 - 5050 of 10000 in total
  1. Target

    Kallikrein-5

    go.drugbank.com/bio_entities/BE0010708
    TargetHumans

    May be involved in desquamation

    Polypeptides: Kallikrein-5
  2. Drug

    Picosulfuric acid

    go.drugbank.com/drugs/DB09268
    ApprovedInvestigational

    Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.[A33322]

    Mixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, AGAROL CON SABOR A FRAMBUESACategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Sodium glycerophosphate

    go.drugbank.com/drugs/DB09561
    Approved

    It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. … The extent of this reaction is dependent on the activity of serum alkaline phosphatases.

    Mixtures: NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 ML, Numeta G 13 % E Emulsion zur InfusionProducts: Glycophos 6 g/20 ml Konzentrat zur Herstellung einer Infusionslösung, GLYCOPHOS CONCENTRATE FOR SOLUTION FOR INFUSION 216 mg/ml
  4. Drug

    Apramycin

    go.drugbank.com/drugs/DB04626
    InvestigationalVet approved

    Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.

    Synonyms: 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine, 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β-(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamineProducts: TP-APRA 500 WSP ApramycinSulphate 500mg/g Water Soluble Powder, APRASURE 50% POWDER
  5. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

    Mixtures: VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADET, VERACOMB MR 180/2 MG KAPSÜL, 28 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin System
  6. Drug

    Tiotropium

    go.drugbank.com/drugs/DB01409
    ApprovedInvestigational

    Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. … [A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.

    Mixtures: SPIOLTO RESPIMAT 2.5 MCG/2.5 MCG INHALASYON ÇÖZELTISI,1 ADET, SALTIF 9/50/100 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  7. Drug

    Digitoxin

    go.drugbank.com/drugs/DB01396
    ApprovedWithdrawn

    A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: Digimerck 0,1 mg/ml - Injektionslösung, Digimerck 0,07 mg - Tabletten
  8. Drug

    Cefditoren

    go.drugbank.com/drugs/DB01066
    Approved

    Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.

    Categories: Heterocyclic Compounds, 2-RingProducts: CEFITEN 50 MG SASE, 21 ADET, CEFITEN 50 MG SASE, 42 ADET
  9. Drug

    Sodium oxybate

    go.drugbank.com/drugs/DB09072
    ApprovedInvestigational

    [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA. … [A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and abuse.

    Products: Natriumoxybat Kalceks 500 mg/ml Lösung zum Einnehmen, Natriumoxybat neuraxpharm 500 mg/ml Lösung zum Einnehmen
  10. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … and mortality in hospitalized patients.

    Mixtures: PIPERACILINA 4000 MG Y TAZOBACTAM 500 MG, ZERBAXA ® 1 G/0.5 GCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring