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Quinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Mixtures: ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADET, ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-RingTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADA, JANTY 5 MG FİLM KAPLI TABLET, 56 ADET4-methylumbelliferyl beta-D-glucoside
go.drugbank.com/drugs/DB13177ExperimentalCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: 7-(beta-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one, 4-methylumbelliferyl β-D-glucosideKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigationalIt has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine]. … Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell stabilizing properties.
Categories: Heterocyclic Compounds, 1-RingProducts: ZADITEN SRO FILM TABLET 2 MG, 30 ADET, U-KEFEN TABLETS 1MGOxolamine
go.drugbank.com/drugs/DB13216ApprovedOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419].
Mixtures: KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADET, KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 MLCategories: Heterocyclic Compounds, 1-RingFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold.
Products: ARIXTRA 7.5 MG/0.6 ML S.C. ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET, ARIXTRA 10 MG/0.8 ML S.C. ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADETHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedFDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy … Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate.
Mixtures: GRAVIDINONA 2 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersChloral hydrate
go.drugbank.com/drugs/DB01563ApprovedIllicitInvestigationalVet approvedThe safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. … A hypnotic and sedative used in the treatment of insomnia.
Products: PMS-CHLORAL HYDRATE SYRUP 500 mg/5 ml, HIDRATO DE CLORAL 10%SOLUCION ORAL(GOTAS)Sultamicillin
go.drugbank.com/drugs/DB12127ApprovedWithdrawnSultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: BACMICINE® 250 MG / 5 ML, BACTESUL 1 G/ 5 MLBifikafusp alfa
go.drugbank.com/drugs/DB19185InvestigationalBifikafusp alfa is under investigation in clinical trial NCT05329792 (L19IL2/L19TNF in Skin Cancer Patients).
Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human interleukin 2