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Brolucizumab
go.drugbank.com/drugs/DB14864ApprovedInvestigationalBrolucizumab, also known as RTH258 or ESBA1008,[A187211] is a monoclonal antibody indicated to treat neovascular age related macular degeneration. … [L9089] Brolucizumab was granted FDA approval in October 2019.[L9089]
Products: Xivubel 120 mg/ml Enjeksiyonluk Çözelti, 1 adet, VSIQQ® SOLUCION INYECTABLEDaclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnThe same dosing regimen can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis. … According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b patients with or without cirrhosis as second-line
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60Anifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigationalAnifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … [A237079,L34929] Three monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that target the type 1 interferon pathway entered clinical trials as potential treatments for systemic lupus
Categories: Type I Interferon Receptor AntagonistProducts: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETStage IV Hodgkin's Disease
go.drugbank.com/conditions/DBCOND0111729Drugs: ProcarbazineSynonyms: Stage 4 Hodgkin's diseaseMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedMethenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: UR N-C Urinary Antiseptic, PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GRProducts: NETURONE GRANUL LIBA, 70 G, NETURONE GRANUL LIBA, 105 GAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalAlogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.
Mixtures: INCRESINA P, OSENI 25 MG/15 MG TABLETSCategories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedAs well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].
Synonyms: 1-(o-Chloro-α,α-diphenylbenzyl)imidazole, 1-(α-(2-Chlorophenyl)benzhydryl)imidazoleMixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, SAEROGENTA-A CREAMRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedIt occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.
Synonyms: Vitamin G, 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitolMixtures: B Plus C 300 mg, COMPLEJO B EN KOLA GRANULADAIndocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalThe chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, … Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: VERDYE 5 mg/ml Injektionszubereitung, ไดแอกโนกรีน(R) ชนิดฉีด 25 มิลลิกรัมEntacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalEntacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. … of levodopa and a decarboxylase inhibitor.
Synonyms: (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide, N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamideMixtures: LEVO/CA/EN 100/25/200 STD, LEVO/CA/EN 150/37.5/200STD