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Displaying results 501 - 510 of 10000 in total
  1. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].

    Mixtures: JANUMET XR TABLET 100MG/1000MG, Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Drugs Used in Diabetes
  2. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [L31178] Although not the first sGC stimulator to be granted FDA approval ([riociguat] was approved in 2013 for use in pulmonary hypertension),[L3955] vericiguat is unique amongst its peers in that modifications … [L31178] Vericiguat was approved by the FDA in January 2021 - developed by Merck under the brand name Verquvo - for use in certain patients with systolic heart failure.

    Categories: Vasodilators Used in Cardiac DiseasesProducts: VERQUVO FILM-COATED TABLET 10MG, VERQUVO® 10MG TABLETAS RECUBIERTAS
  3. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    This effect can be beneficial, however, as dose-related side effects such as respiratory depression, sedation, and intoxication also plateau at around 32mg, resulting in a lower risk of overdose compared … [A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such

    Mixtures: BUPRENORFINA E NALOXONE ETHYPHARM, BUPRENORFINA E NALOXONE ETHYPHARMCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders
  4. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals

    Mixtures: FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDO, FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDOCategories: Agents Acting on the Renin-Angiotensin System
  5. Drug

    Ciprofloxacin

    go.drugbank.com/drugs/DB00537
    ApprovedInvestigational

    [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]

    Products: . - Liq 10mg/ml, Cipro IV 10mg/ml
  6. Drug

    Fluspirilene

    go.drugbank.com/drugs/DB04842
    ApprovedWithdrawn

    A long-acting injectable antipsychotic agent used for chronic schizophrenia.

    Products: Imap Forte Inj 10mg/ml
  7. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [L32283] In addition, oral ketotifen is used in Mexico and across Europe for the treatment of various allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. … available and indicated as an add-on therapy for children with atopic asthma.

    Products: KETOTIFENE EG, Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen
  8. Drug

    Secukinumab

    go.drugbank.com/drugs/DB09029
    ApprovedInvestigational

    [A249840] Following its first global approval in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and by the FDA a few days after (January 21, 2015). … Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque

    Products: Fraizeron 150mg/ml solution for injection in pre-filled pen, COSENTYX SOLUTION FOR INJECTION IN PREFILLED SENSOREADY PEN 150MG/ML
  9. Drug

    Selumetinib

    go.drugbank.com/drugs/DB11689
    ApprovedInvestigational

    [A193533,A193608] While some patients with this disorder develop PNs, this is considered relatively uncommon compared to other variants of NF-1. … [A193608] Use of selumetinib in this population has shown efficacy in shrinking associated tumours and is linked to other positive clinical outcomes.

    Products: KOSELUGO HARD CAPSULES 10MG
  10. Drug

    Lansoprazole

    go.drugbank.com/drugs/DB00448
    ApprovedInvestigational

    [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)

    Products: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADA