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Displaying results 501 - 510 of 10000 in total
  1. Drug

    Tenecteplase

    go.drugbank.com/drugs/DB00031
    ApprovedInvestigational

    It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids … 296-299 in the protease domain.

    Products: METALYSE FOR INJECTION 10,000 u/vial, METALYSE®10.000 U (50MG) POLVO LIOFILIZADO PARA SOLUCION INYECTABLE
  2. Drug

    Valproate bismuth

    go.drugbank.com/drugs/DB13910
    Approved

    Valproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Neo-laryngobis, Neo Laryngobis Enf
  3. Drug

    Evening primrose oil

    go.drugbank.com/drugs/DB11358
    ApprovedNutraceutical

    [A33131] Evening primrose oil has been filled for the FDA by Humanetics Corporation on April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of safety". … Evening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used as an alternative source for omega-6 essential fatty acids.

    Mixtures: Efamol Cap, Evening Primrose Oil CapCategories: Fatty Acids, Omega-6, Cytochrome P-450 CYP2C19 Inhibitors
  4. Drug

    Chromium

    go.drugbank.com/drugs/DB11136
    ApprovedInvestigational

    Humans can be exposed to chromium via ingestion, inhalation, and dermal or ocular exposure [L1983]. … Trivalent chromium (Cr(III)) ion is considered to be an essential dietary trace element as it is involved in metabolism of blood glucose, regulation of insulin resistance and metabolism of lipids.

    Mixtures: Spectrum 2 Cap, ADDAMEL NProducts: Ionochrome Cap 10mcg, Chrome Zme (ii)
  5. Drug

    Cisatracurium

    go.drugbank.com/drugs/DB00565
    ApprovedInvestigational

    Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. … Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.

    Synonyms: (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Oxytocin

    go.drugbank.com/drugs/DB00107
    ApprovedInvestigationalVet approved

    [A229108] Oxytocin continues to be an important tool in modern obstetrics to induce labor when indicated and to manage postpartum hemorrhage. … [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning.

    Mixtures: Bakumokon 5% Minoxidil, Bakumokon 7% Minoxidil SulfateProducts: OXITOCINA 10 UI, OXITOCINA INYECCION 10 UI
  7. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester, isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  8. Indication

    No primary neurological disease, idiopathic decreased mental activity

    go.drugbank.com/conditions/DBCOND0141360
    Drugs: Dihydro-alpha-ergocryptine · Dihydroergocornine · Dihydroergocristine · Epicriptine
    Synonyms: No primary neurological disease, idiopathic decreased mental activity, No primary neurologial disease, idiopathic decreased mental activity
  9. Drug

    Metamizole

    go.drugbank.com/drugs/DB04817
    ApprovedInvestigationalWithdrawn

    [L42975] In 1963, metamizole was withdrawn from the Canadian market and banned in the UK, France, Sweden, Norway and Australia. … [A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to its association with potentially fatal agranulocytosis

    International brands: Neo-MelubrinaMixtures: BIPASMIN COMPUESTO N, BIPASMIN COMPUESTO N
  10. Drug

    Hydrocortisone acetate

    go.drugbank.com/drugs/DB14539
    ApprovedInvestigationalVet approved

    Synonyms: 21-O-acetylcortisolMixtures: Alumier MD Post Procedure Prescription, No-SCAR Oint.