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4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE
go.drugbank.com/drugs/DB07687ExperimentalSynonyms: 4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDEBMS-770767
go.drugbank.com/drugs/DB18902InvestigationalBMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).
Synonyms: 4-(8-(2-CHLOROPHENOXY)(1,2,4)TRIAZOLO(4,3-A)PYRIDIN-3-YL)BICYCLO(2.2.1)HEPTAN-1-OL, BICYCLO(2.2.1)HEPTAN-1-OL, 4-(8-(2-CHLOROPHENOXY)-1,2,4-TRIAZOLO(4,3-A)PYRIDIN-3-YL)-Categories: Heterocyclic Compounds, 1-RingSotatercept
go.drugbank.com/drugs/DB12118ApprovedInvestigationalIt is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. … Sotatercept is an activin signalling inhibitor.
Synonyms: (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-Categories: Immunoglobulin G4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide
go.drugbank.com/drugs/DB01888ExperimentalSynonyms: 4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-DimethylbenzenesulfonamideN-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
go.drugbank.com/drugs/DB08362ExperimentalSynonyms: N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDEEquecabtagene autoleucel
go.drugbank.com/drugs/DB19016InvestigationalSynonyms: autologous T lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis, transduced with a self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (, CAR) targeting human B cell maturation antigen (BCMA)DPA-714 F-18
go.drugbank.com/drugs/DB19189InvestigationalSynonyms: N,n-diethyl-(2-(4-(2-(18f)fluoroethoxy)phenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidine-3-yl)acetamide, Pyrazolo(1,5-a)pyrimidine-3-acetamide, n,n-diethyl-2-(4-(2-(fluoro-18f)ethoxy)phenyl)-5,7-dimethyl-Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Synonyms: Cl-F-Ara-A, (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-olCategories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexNNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalIt was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019. … NNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been
Synonyms: Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)-, Cyclo(-L-glycyl-L-2-allylproline)Categories: Heterocyclic Compounds, 1-Ring2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide
go.drugbank.com/drugs/DB08026ExperimentalSynonyms: 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide