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Bedaquiline
go.drugbank.com/drugs/DB08903ApprovedInvestigational[A261856,A261861] It is the first drug that was approved in the last 40 years by the FDA for TB unresponsive to current treatments on the market. … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB
Fondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalThe monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII). … Fondaparinux may be used: to prevent venous thromboembolism in patients who have undergone orthopedic surgery of the lower limbs (e.g. hip fracture, hip replacement and knee surgery); to prevent VTE in
Prasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalPrasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. … DHEA and DHEAS are readily available in the United States, where they are marketed as over-the-counter dietary supplements.
Categories: Sex Hormones and Modulators of the Genital SystemHydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalStructurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[T90] The derivatives of this fungus are identified to be about 350 different substances from which the components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives … [L2640] To know more about the individual components of the ergoloid mixture, please visit [DB11275], [DB11274], [DB11273] and [DB13345].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFlavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigational[A274616,L54226] FMN is composed of an isoalloxazine ring - which serves as the active redox center - attached to a ribityl phosphate chain. … Flavin mononucleotide (FMN), also known as riboflavin 5'-phosphate, is one of the two major coenzymes derived from [riboflavin] (vitamin B2) and is one of the principal forms in which dietary riboflavin
Mixtures: Multivit Et Fer Ampoules Et Comprimes, Dynam Ampoule Et TabletArginine
go.drugbank.com/drugs/DB00125ApprovedInvestigationalNutraceuticalAn essential amino acid that is physiologically active in the L-form.
Mixtures: Clinimix E, Clinimix EIsoniazid
go.drugbank.com/drugs/DB00951ApprovedInvestigationalIt remains the treatment of choice for tuberculosis.
Mixtures: TB VIT 6, PRO TB 4Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedThe main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units. … When labelled with technetium Tc99m, dextran 75 is intravenously administered as an imaging agent to detect and diagnose conditions in the vascular compartment such as pericardial effusion or ventricular
Mixtures: BIOFLEKS %10 DEKSTRAN-40 %0,9 IZOTONIK SODYUM KLORUR ÇÖZELTİSİ (PVC TORBA) 500 ML VE SETLIProducts: DEKSTRAN 40 İE (SETLİ), DEKSTRAN 70 İE (SETLİ)