Search
Fluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase.
Categories: Heterocyclic Compounds, 2-RingProducts: Fluvastatin Sandoz 20 mg - Hartkapseln, LESCOL XL 80 MG TABLET, 28 ADETCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigationalCarboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Categories: Compounds used in a research, industrial, or household settingSynonyms: Platinum, diammine [1,1-cyclobutane-dicarboxylato(2-)-0,0']-,(SP-4-2)Octreotide
go.drugbank.com/drugs/DB00104ApprovedInvestigationalOn June 26, 2020, the first approved delayed-release oral somatostatin analog, Mycapssa, received FDA approval for the long term maintenance treatment of acromegaly. … [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor.
Products: SANDOSTATIN LAR 20 MG., SANDOSTATIN LAR 10 MGLercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnLercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Mixtures: LERCAPREL 20 MG/10 MG, Zanipril 20 mg/10 mg FilmtablettenCategories: Heterocyclic Compounds, 1-RingDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigational[L10556] Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and [verapamil] that directly acts on the heart muscle, diltiazem displays an intermediate … , and rest-related cramps in the lower extremities.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetateAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: Osmolex ER, Osmolex ERCategories: M2 Protein Inhibitors, Influenza A M2 Protein InhibitorBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320]
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLCategories: Heterocyclic Compounds, 1-RingPiperazine
go.drugbank.com/drugs/DB00592ApprovedVet approvedWithdrawnPiperazine was first introduced as an anthelmintic in 1953. … First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953.
Categories: Heterocyclic Compounds, 1-RingProducts: PIPERAZINA AL 20%, PIPERAZINA AL 10%Piracetam
go.drugbank.com/drugs/DB09210ApprovedWithdrawnPiracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. … It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA).
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingProducts: NECETAM 1200 MG FİLM TABLET, 20 TABLET, DEXPIRA 20%Lansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Mixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, LACOMBI 30/10 MG KAPSUL, 28 ADETCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring