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5-O-phosphono-alpha-D-ribofuranosyl diphosphate
go.drugbank.com/drugs/DB01632ApprovedWithdrawnThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Ragweed pollen extract
go.drugbank.com/drugs/DB05368ApprovedWithdrawnThe company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy.
Brasofensine
go.drugbank.com/drugs/DB04857ExperimentalBrasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K. … In November 2001, NeuroSearch confirmed that the drug's development was discontinued in favor of NS 2230.
Iohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIts low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
MC-1
go.drugbank.com/drugs/DB05315ExperimentalMedicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.
Lancovutide
go.drugbank.com/drugs/DB05029InvestigationalLancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is closely related to cinnamycin (Ro09-0198). It belongs to the lantibiotics. … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis.
IR501
go.drugbank.com/drugs/DB06464ExperimentalIt was last known to be in phase III clinical trials. … IR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity.
Ezatiostat
go.drugbank.com/drugs/DB05460InvestigationalThis compound belongs to the peptides. … These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen
Surotomycin
go.drugbank.com/drugs/DB12076InvestigationalDifficile and other Gram-positive bacteria with minimal impact on the Gram-negative organisms of the intestinal microbiota. … Surotomycin, given orally, has been shown to be highly effective against both initial and relapsing hamster Clostridium difficile-associated diarrhea, with a potency similar to vancomycin.