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Displaying results 5121 - 5130 of 10000 in total
  1. Drug

    Bimoclomol

    go.drugbank.com/drugs/DB06258
    Experimental

    Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Mitoquinone

    go.drugbank.com/drugs/DB05063
    Investigational

    In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct molecular link between mitochondrial dysfunction and the pathogenesis of Parkinson's disease. … Mitochondrial dysfunction also has been shown to represent an early critical event in the pathogenesis of the sporadic form of Parkinson's disease.

    Synonyms: Mitoquinone ion
  3. Drug

    Epinastine

    go.drugbank.com/drugs/DB00751
    Approved

    It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … Epinastine is used for the prevention of itching associated with allergic conjunctivitis.

    Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADACategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  4. Drug

    cryopreserved human liver cells

    go.drugbank.com/drugs/DB05852
    Experimental

    Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. … The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation

  5. Drug

    Alfimeprase

    go.drugbank.com/drugs/DB04919
    Investigational

    It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo. … Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (<i>Agkistrodon contortrix contortrix</i>).

    Synonyms: 3-203-FIBROLASE (3-SERINE) (AGKISTRODON CONTORTRIX CONTORTRIX RECOMBINANT)
  6. Drug

    Arachidonic Acid

    go.drugbank.com/drugs/DB04557
    ApprovedInvestigationalWithdrawn

    An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. … It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem]

    Mixtures: SIMILAC ALIMENTUM 400 G TOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  7. Drug

    Iocarmic acid

    go.drugbank.com/drugs/DB13755
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated
  8. Drug

    Tesofensine

    go.drugbank.com/drugs/DB06156
    Investigational

  9. Drug

    PI-166

    go.drugbank.com/drugs/DB05859
    Experimental

    PI-166 is a small organic compound with specific avidity to liver cancer cells. … It has demonstrated the ability to reduce the growth of rat hepatomas, which is like human hepatomas, are resistant to established anti-cancer agents.

  10. Drug

    Trimoprostil

    go.drugbank.com/drugs/DB19935
    Experimental

    Trimoprostil is a small molecule drug. The usage of the INN stem '-prostil' in the name indicates that Trimoprostil is a anti-ulcer prostaglandin. … Trimoprostil has a monoisotopic molecular weight of 378.28 Da.

    Categories: Prostaglandins E