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Displaying results 5131 - 5140 of 8974 in total
  1. Drug

    Elacridar

    go.drugbank.com/drugs/DB04881
    Investigational

    Development is assumed to have been discontinued. … In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline.

  2. Drug

    Ravidasvir

    go.drugbank.com/drugs/DB15652
    Investigational

    Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  3. Drug

    PI-0824

    go.drugbank.com/drugs/DB05516
    Investigational

    The goal of this therapy is to reduce the production of antibodies that cause PV blisters by acting only on the disease causing components of the immune system. … Peptimmune, Inc. has developed a new therapy for the treatment of PV, PI-0824.

  4. Drug

    INCB7839

    go.drugbank.com/drugs/DB05033
    Investigational

    INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways.

  5. Drug

    LU-31130

    go.drugbank.com/drugs/DB05828
    Experimental

    LU-31130 is a rapid acting therapy developed by H. Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. … It acts at the Dopamine D4 receptors in the cortex and has low affinity for D2 receptors, adrenoceptors, muscarinic and histaminergic receptors.

  6. Drug

    Rivoglitazone

    go.drugbank.com/drugs/DB09200
    Investigational

    Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co.

  7. Drug

    Sulfaisodimidine

    go.drugbank.com/drugs/DB13283
    Experimental

    officially approved for use anywhere [A175672]. … Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Spermine

    go.drugbank.com/drugs/DB00127
    InvestigationalNutraceutical

    Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.

  9. Indication

    Mucopolysaccharidosis Type I (MPS I)

    go.drugbank.com/conditions/DBCOND0065667
    Drugs: Laronidase
    Synonyms: Mucopolysaccharidosis type I severe form, Mucopolysaccharidosis type I mild form
  10. Drug

    Terizidone

    go.drugbank.com/drugs/DB12954
    ApprovedInvestigationalWithdrawn

    Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.

    Categories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis