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Gimeracil
go.drugbank.com/drugs/DB09257ApprovedInvestigationalApproved by the European Medicines Agency (EMA) in March 2011, Gimeracil is available in combination with [DB03209] and [DB09256] within the commercially available product "Teysuno". … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.
Mixtures: TS-ONE CAPSULE 20, TS-ONE CAPSULE 20Categories: Heterocyclic Compounds, 1-RingBemiparin
go.drugbank.com/drugs/DB09258ApprovedInvestigationalWithdrawnLike semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH).
Products: HIBOR 10000 IU/0,4 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET, HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADETIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedIdarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease
Products: PRAXBIND®, PRAXBİND 50 MG/ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADETPicosulfuric acid
go.drugbank.com/drugs/DB09268ApprovedInvestigationalPicosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.[A33322]
Mixtures: CITRAFLEET 0.01 G/ 3.50 G/ 10.97 G ORAL ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN SAŞE , 2 ADET, PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞECategories: Heterocyclic Compounds, 1-RingDoxofylline
go.drugbank.com/drugs/DB09273InvestigationalDoxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. … Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169].
Mixtures: MUCOFIX 600/200 MG EFERVESAN, 5 ADET, MUCOFIX 1200/400 MG EFERVESAN TABLET, 5 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor AgonistsSodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnSodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. … Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Products: MYOCRISIN INJECTION 20 MG (4% W/V)Imolamine
go.drugbank.com/drugs/DB09284InvestigationalIt is developed under the brand name Coremax by Novartis consumer health SA. … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazolPropacetamol
go.drugbank.com/drugs/DB09288InvestigationalPropacetamol is a parenteral formulation of paracetamol and thus, it is a prodrug that is completely hydrolyzed to paracetamol. … [A32051] It is a derivative of [acetaminophen], or paracetamol, with the molecular formula glycine, N, N-diethyl-,4-(acetylamino)phenyl ester.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesRamosetron
go.drugbank.com/drugs/DB09290InvestigationalRamosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. … It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: IRRIBOW TABLET 5 MCG, NASEA(R) TABLET 0.1 MGRolapitant
go.drugbank.com/drugs/DB09291ApprovedInvestigationalNeurokinin-1 is also known as Tachykinin Receptor 1 (TACR1), Neurokinin 1 Receptor (NK1R), and Substance P Receptor (SPR). … Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults.
Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists