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SQ-109
go.drugbank.com/drugs/DB05186InvestigationalSQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. … Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen.
99mTc-glucarate
go.drugbank.com/drugs/DB05810Investigational99mTc-glucarate(GLA) is an agent for non-invasive detection of breast tumours.
AT-301
go.drugbank.com/drugs/DB16507InvestigationalAT-301 was under investigation in clinical trial NCT01675284 to evaluate the safety, reactogenicity, and humoral immune responses to an inactivated H5N1 influenza vaccine
N,N'-diphenyl-1,4-phenylenediamine
go.drugbank.com/drugs/DB14192ApprovedCategories: Compounds used in a research, industrial, or household settingBentonite
go.drugbank.com/drugs/DB11306ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingAPT3111
go.drugbank.com/drugs/DB06390ExperimentalAPT3111 is an investigational drug used to treat PNH (paroxysmal nocturnal haemoglobinurea).
Sodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnIt is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis. … Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects.
Transforming growth factor beta activator LRRC32
go.drugbank.com/bio_entities/BE0014554TargetHumansKey regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19651619, PubMed:19750484, PubMed:22278742). As...
Synonyms: Leucine-rich repeat-containing protein 32Function: receptor ligand inhibitor activityNatural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalIt is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells. … Generally, the number of NK cells collected in the peripheral blood mononuclear cell (PBMC) is too low for sufficient potency, and ex vivo expansion is performed.
Synonyms: NK CellsPamapimod
go.drugbank.com/drugs/DB19169InvestigationalPamapimod is under investigation in clinical trial NCT05659459 (The KIN-FAST Trial (KIN001 for Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With Sars-cov-2).