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Zotiraciclib
go.drugbank.com/drugs/DB16656InvestigationalZotiraciclib is under investigation in clinical trial NCT02942264 (Zotiraciclib (TG02) Plus Dose-dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide
EW-A-401
go.drugbank.com/drugs/DB05525InvestigationalThis specific transcription factor has been shown in animal studies to increase expression of the VEGF-A gene, and to promote the growth of new blood vessels. … EW-A-401 is a circle of genetic material (plasmid DNA) that instructs the body to produce a genetically-engineered transcription factor, a protein that regulates expression of genes.
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. … A study in 2013 showed that CO-administration of polaprezinc may be effective against small intestine mucosal injury associated with long-term aspirin therapy [A7840].
LY-517717
go.drugbank.com/drugs/DB05713InvestigationalIt is believed to be Lilly's PMD-3112 (licensed from Amgen).
BMS-986141
go.drugbank.com/drugs/DB14942InvestigationalBMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
V116517
go.drugbank.com/drugs/DB16060InvestigationalV116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
ETC-1001
go.drugbank.com/drugs/DB05866ExperimentalETC-1001 is Pfizer’s lead oral small molecule product candidate which is intended to be a chronic treatment for individuals with lipid disorders.
SB-269970
go.drugbank.com/drugs/DB13988ExperimentalSB-269970 is an experimental drug developed by GlaxoSmithKline.
Prostaglandin D2
go.drugbank.com/drugs/DB02056ExperimentalIt is released upon activation of mast cells and is also synthesized by alveolar macrophages.
NSI-566
go.drugbank.com/drugs/DB17954InvestigationalDeveloped by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).[L47097]