Prostaglandin D2

DB02056ExperimentalSmall molecule

The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important...

Chemical structure of Prostaglandin D2
Mechanism
Curator reviewed
Formula / weight
C20H32O5 · 352.4651 g/mol (avg)
Also known as
PGD2

Resolves to

Compound
UNIIRXY07S6CZ2CAS41598-07-6ChEMBLCHEMBL1235252ChEBI15555PubChem448457KEGGC00696
Structure
InChIKeyBHMBVRSPMRCCGG-OUTUXVNYSA-NSMILES[H][C@](O)(CCCCC)\C=C\[C@@]1([H])C(=O)C[C@]([H])(O)[C@]1([H])C\C=C/CCCC(O)=O
Targets
Q9Y5Y4PTGDR2P43116PTGER2P43115PTGER3P34995PTGER1P43088PTGFRP35408PTGER4Q13258PTGDRP42330AKR1C3
Transporters
Q92959SLCO2A1

What you can answer from here — as of September 13, 2026

8Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
106Drug interactionsStructured to mechanism, not free text
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Prostaglandin D2, and which of those have an active Phase 3 trial?

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