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Buspirone
go.drugbank.com/drugs/DB00490ApprovedInvestigationalBuspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. … Belonging to the azaspirodecanedione drug class,[A180991] buspirone is a serotonin 5-HT<sub>1A</sub> receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dioneEntacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalEntacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. … of levodopa and a decarboxylase inhibitor.
Mixtures: LEVO C/E BETA100/25/200, LEVO C/E BETA100/25/200Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsFlutamide
go.drugbank.com/drugs/DB00499ApprovedInvestigationalAn antiandrogen with about the same potency as cyproterone in rodent and canine species.
Synonyms: α,α,α-trifluoro-2-methyl-4'-nitro-m-propionotoluidide, 4'-nitro-3'-trifluoromethylisobutyranilideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalHaloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. … [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-oneTridihexethyl
go.drugbank.com/drugs/DB00505ApprovedWithdrawnTridihexethyl is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Dextrothyroxine
go.drugbank.com/drugs/DB00509ApprovedWithdrawnThyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism.
Synonyms: O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine, D-thyroxineAcetyldigitoxin
go.drugbank.com/drugs/DB00511ApprovedCardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Desglucolanatoside A, Digitoxin 3'''-acetateVancomycin
go.drugbank.com/drugs/DB00512ApprovedInvestigationalIt is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: PMS-vancomycin 1 G, VANCOMICINA 1 G/ VIALAminocaproic acid
go.drugbank.com/drugs/DB00513ApprovedInvestigationalAn antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Mixtures: NAVI Black and C-Clinic, Relief and Nature Toothpast E Jasmine MintSynonyms: 6-Aminocaproic acid, 6-aminohexanoic acidCisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalCisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-