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Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
go.drugbank.com/bio_entities/BE0000087TargetHumansPart of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine r...
Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1Apixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban was approved by the FDA on December 28, 2012[L6043].
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ELIQUIS® 5 MG, APICOG-5 (Apixaban Film Coated Tablets 5 mg)Vortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalreceptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT1 Receptor AntagonistsProducts: KELAC 5 MG, SORDENA 5 MG FİLM KAPLI TABLET , 28 ADETRaltitrexed
go.drugbank.com/drugs/DB00293ApprovedInvestigationalRaltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: TOMUDEX ® 2 MG, TOMUDEX 2 MG FLAKON, 1 ADETCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.
Mixtures: DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAK, Dfs 1.5%/ms 25%/menth 6%/cap 0.025% PakCategories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: ZOVILAM PED DT®, LAMIVUDINA E ZIDOVUDINA MYLANCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalOne of the most common uses for this drug is for a condition called _allergic rhinitis_. … Cetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal
Mixtures: ACERADOX® G, Zyrtec-DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesPeanut
go.drugbank.com/drugs/DB10553ApprovedPeanut allergenic extract is used in allergenic testing.
Mixtures: PALFORZIA (Level 3), PALFORZIA (Level 3)Products: PALFORZIA (Level 2), PALFORZIA (Level 5)Ursodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigationalUrsodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. … [A256272] Due to its hydrophilicity, UDCA is less toxic than [cholic acid] or [chenodeoxycholic acid].
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (3α,5β,7β)-3,7-dihydroxycholan-24-oic acid, 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acidBoric acid
go.drugbank.com/drugs/DB11326ApprovedInvestigationalBoric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3.
Mixtures: Recal D, DERIVERIN MERHEM, 25 GCategories: Compounds used in a research, industrial, or household setting