Search

Displaying results 5191 - 5200 of 10000 in total
  1. Target

    5-hydroxytryptamine receptor 3D

    go.drugbank.com/bio_entities/BE0009585
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3DSynonyms: 5-HT3D, 5-HT3-D
  2. Drug

    Blinatumomab

    go.drugbank.com/drugs/DB09052
    ApprovedInvestigational

    Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through … a short peptide linker.

    Categories: Bispecific CD19-directed CD3-directed T Cell EngagerProducts: BLİNCYTO 38,5 MCG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ VE ÇÖZELTİ, 1 ADET, BLINCYTO® 38.5 MCG/VIAL
  3. Drug

    Opium

    go.drugbank.com/drugs/DB11130
    ApprovedIllicit

    It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. … [A32175] Opium is a prohibited drug of abuse in most countries, but the illegal production of this drug and its derivatives keeps being registered.

    Mixtures: Donnagel-PG Liq, Donnagel-PG CapCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Iron Dextran

    go.drugbank.com/drugs/DB00893
    ApprovedInvestigationalVet approved

    Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. … Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.

    Mixtures: Irospan 24/6Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Exametazime

    go.drugbank.com/drugs/DB11179
    Approved

    It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection.

    Products: CERETEC FOR INJECTION 0.5 mg/vial, BRAIN - SPECT®
  6. Drug

    Potassium acetate

    go.drugbank.com/drugs/DB14498
    Approved

    Mixtures: Normosol-M & 5% Dextrose, AMINOPLASMAL-5% E INFUSIONProducts: DBL POTASSIUM ACETATE CONCENTRATED INJECTION 2.45 g/5 ml, Potassium Acetate Inj 2meq/ml
  7. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    The most common critical NS5A amino acid substitutions that led to reduced susceptibility to daclatasvir therapy occured at position Q30 (Q30H/K/R) and M28 in genotype 1a patients and Y93H in genotype … Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60
  8. Drug

    Gadoxetic acid

    go.drugbank.com/drugs/DB08884
    ApprovedInvestigational

    Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. … Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection.

    Categories: Compounds used in a research, industrial, or household settingProducts: PRIMOVIST 0,25 MMOL/ML ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET, PRIMOVIST® SOLUCIÓN INYECTABLE
  9. Drug

    Ecallantide

    go.drugbank.com/drugs/DB05311
    Approved

    By reversibly binding to plasma kallikrein, ecallantide displays a rapid on-rate and a slow off-rate that results in high affinity inhibition in the picomolar range [L1458]. … Hereditary angioedema is a rare autosomal dominant disorder with mutations to C1-esterase-inhibitor (C1-INH) located on Chromosome 11q, resulting in substantially lower levels of C4 and C1-INH activity

    Categories: Drugs Used in Hereditary AngioedemaProducts: KALBITOR® 10 MG / ML
  10. Drug

    Tin protoporphyrin IX

    go.drugbank.com/drugs/DB16449
    Investigational

    Synonyms: Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κ<sup>21</sup>,κN<sup>22</sup>,κN<sup>23</sup>,κN<sup>24</sup>]-, hydrogen (1:2), (OC-6-13)-, Dihydrogen (OC-6-13)-dichloro[7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropionato(4-)-N<sup>21</sup>,N<sup>22</sup>,N<sup>23</sup>,N<sup>24</sup>]stannate(2-)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings