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Pentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is a vasodilator with properties that are quite similar to those of glyceryl trinitrate, however, with a more prolonged duration of action. … Interestingly, this drug was studied for potential benefits in chronic ischemic heart failure patients.
Products: Peritrate Sa 80mg TabActoxumab
go.drugbank.com/drugs/DB16376InvestigationalActoxumab is under investigation in clinical trial NCT01241552 (A Study of MK-3415, MK-6072, and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-001)
ALMB-0166
go.drugbank.com/drugs/DB17937InvestigationalALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.[L47067]
Chimeric antigen receptor T-cells
go.drugbank.com/drugs/DB22146InvestigationalChimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian
Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Hydroxyethylpromethazine
go.drugbank.com/drugs/DB13840ExperimentalCategories: Antihistamines for Systemic UseIDM-2
go.drugbank.com/drugs/DB05293ExperimentalIDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells. IDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.
Quinidine barbiturate
go.drugbank.com/drugs/DB01346ApprovedA papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)
Neladalkib
go.drugbank.com/drugs/DB21712InvestigationalNeladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC). … Neladalkib has a monoisotopic molecular weight of 452.15 Da.
Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)