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Pentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is a vasodilator with properties that are quite similar to those of glyceryl trinitrate, however, with a more prolonged duration of action. … Interestingly, this drug was studied for potential benefits in chronic ischemic heart failure patients.
Products: Peritrate Sa 80mg TabAGS-004
go.drugbank.com/drugs/DB05742InvestigationalA personalized immunotherapy addresses these issues because it is able to capture private viral mutations, providing a matched, complete immune response for each individual HIV patient. … This approach may overcome the weaknesses of other available therapies and therefore could result in a better chance of success for HIV treatment.
Bavituximab
go.drugbank.com/drugs/DB05136InvestigationalBavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections.
Brontictuzumab
go.drugbank.com/drugs/DB12737InvestigationalBrontictuzumab has been used in trials studying the treatment of Adenoid Cystic Carcinoma, Relapsed or Refractory Solid Tumors, and Relapsed or Refractory Lymphoid Malignancies.
Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.
Nifurtoinol
go.drugbank.com/drugs/DB13730ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseIDM-2
go.drugbank.com/drugs/DB05293ExperimentalIDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells. IDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.
LSZ-102
go.drugbank.com/drugs/DB15362InvestigationalLSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Atabecestat
go.drugbank.com/drugs/DB15307InvestigationalAtabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9,
ABP-700
go.drugbank.com/drugs/DB15411InvestigationalABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy
Categories: GABA-A Receptor Agonists