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Displaying results 5211 - 5220 of 10000 in total
  1. Drug

    Promegestone

    go.drugbank.com/drugs/DB13602
    Experimental

    Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 Substrates
  2. Drug

    Phenazocine

    go.drugbank.com/drugs/DB13606
    Experimental

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  3. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

    Synonyms: Nucleic acid aptamer binding to tumor cell nucleon
  4. Drug

    Dexpramipexole

    go.drugbank.com/drugs/DB15130
    Investigational

    From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)). … Dexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  5. Drug

    SQ-109

    go.drugbank.com/drugs/DB05186
    Investigational

    SQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. … Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten the TB treatment regimen.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-adamantanyl-N'-geranyl-ethylenediamine
  6. Drug

    Interferon alfa

    go.drugbank.com/drugs/DB05258
    ApprovedInvestigationalWithdrawn

    Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. … Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.

    Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: IFN-α, HuIFN-alpha-Le
  7. Drug

    (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol

    go.drugbank.com/drugs/DB06943
    Experimental

    These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17. … (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides.

    Synonyms: (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
  8. Drug

    Ritiometan

    go.drugbank.com/drugs/DB13267
    Approved

    Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.

  9. Drug

    Clevidipine

    go.drugbank.com/drugs/DB04920
    ApprovedInvestigational

    Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  10. Drug

    Phloxine B

    go.drugbank.com/drugs/DB13911
    ApprovedWithdrawn

    Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing … These tablets allow patients to visualise areas where more brushing and flossing are needed.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: D&C Red No. 28, Disodium 2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein