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Biapenem
go.drugbank.com/drugs/DB13028InvestigationalBiapenem has been used in trials studying the treatment of various bacterial infections. It is a carbapenem antibiotic with a methyl group on the 1-beta position, which gives it stability against degradation by dehydropeptidase I.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseNifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigationalNifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].
Categories: Antihypertensive Agents Indicated for HypertensionProducts: ADALAT CAPSULAS POR 10 MGMerimepodib
go.drugbank.com/drugs/DB04862InvestigationalMerimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH. Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.
Loprazolam
go.drugbank.com/drugs/DB13643ExperimentalIt is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.
CTA30X UCAR-T
go.drugbank.com/drugs/DB24819InvestigationalCTA30X UCAR-T is under investigation in clinical trial NCT05015972 (UCAR-T for CD19+ Refractory/Relapsed B Hematologic Malignancies).
TORL-2-307
go.drugbank.com/drugs/DB18376ExperimentalTORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin 18.2 (CLDN18.2) being investigated for the treatment of gastric and pancreatic cancer.
Ozekibart
go.drugbank.com/drugs/DB18675InvestigationalIt is being investigated for the treatment of chondrosarcoma.
Pamapimod
go.drugbank.com/drugs/DB19169InvestigationalPamapimod is under investigation in clinical trial NCT05659459 (The KIN-FAST Trial (KIN001 for Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With Sars-cov-2).
Tigozertinib
go.drugbank.com/drugs/DB19239InvestigationalTigozertinib (BLU-945) is currently under investigation in clinical trial NCT04862780 (Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC) for the treatment of NSCLC.
Opiranserin
go.drugbank.com/drugs/DB16271InvestigationalOpiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).