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Displaying results 5231 - 5240 of 10000 in total
  1. Drug

    GI heptapeptide

    go.drugbank.com/drugs/DB15070
    Investigational

    GI heptapeptide is under investigation in clinical trial NCT01391208 (Esophageal Protocol for Detection of Neoplasia in the Digestive Tract).

    Synonyms: GI heptapeptide
  2. Drug

    Pyrimethamine

    go.drugbank.com/drugs/DB00205
    ApprovedInvestigationalVet approved

    One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

    Synonyms: 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidineCategories: MATE 1 Inhibitors, MATE 2 Inhibitors
  3. Drug

    SR 140333

    go.drugbank.com/drugs/DB05790
    Experimental

    SR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Adrafinil

    go.drugbank.com/drugs/DB08925
    ApprovedWithdrawn

    Adrafinil is a mild central nervous system stimulating drug typically employed to relieve excessive sleepiness and inattention in geriatric patients. … Adrafinil is metabolized to [modafinil].

  5. Drug

    Human papillomavirus type 6 L1 capsid protein antigen

    go.drugbank.com/drugs/DB10299
    ApprovedInvestigational

    Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18.

    Synonyms: L1 protein, Human papillomavirus type 6 Vaccine, Human papillomavirus type 6 L1 capsid protein antigenMixtures: Gardasil 9, GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE
  6. Drug

    Disulfiram

    go.drugbank.com/drugs/DB00822
    ApprovedInvestigational

    A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. … When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension,

    Synonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Gemogenovatucel-T

    go.drugbank.com/drugs/DB17412
    Investigational

    Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.

    Synonyms: Gemogenovatucel-T
  8. Drug

    Clothiapine

    go.drugbank.com/drugs/DB13256
    Approved

    Clothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.

    Categories: Heterocyclic Compounds, 3-Ring
  9. Drug

    Col-Treg

    go.drugbank.com/drugs/DB18451
    Experimental

    Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.[A261635]

    Synonyms: Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen
  10. Drug

    Danburstotug

    go.drugbank.com/drugs/DB19064
    Investigational

    Danburstotug is under investigation in clinical trial NCT04809012 (Study of STI-3031 in Patients With Selected Relapsed or Refractory Solid Tumors).

    Synonyms: Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal sti-3031 .gamma.1-chain), disulfide with human monoclonal sti-3031 .lambda.-chain, dimer