Human papillomavirus type 6 L1 capsid protein antigen
Identification
- Brand Names
- Gardasil, Gardasil 9
- Generic Name
- Human papillomavirus type 6 L1 capsid protein antigen
- DrugBank Accession Number
- DB10299
- Background
Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18. The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant Saccharomyces cerevisiae and self-assembled into VLPs.
- Type
- Biotech
- Groups
- Approved, Investigational
- Biologic Classification
- Vaccines
Other vaccines - Synonyms
- L1 protein, Human papillomavirus type 6 Vaccine
- Recombinant human papillomavirus type 6 L1 protein
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Contraindications & Blackbox Warnings
- Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 ug/0.5mL) + Human papillomavirus type 11 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 16 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 18 L1 capsid protein antigen (20 ug/0.5mL) Injection, suspension Intramuscular Merck Sharp & Dohme Llc 2006-06-08 Not applicable US Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 ug/0.5mL) + Human papillomavirus type 11 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 16 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 18 L1 capsid protein antigen (20 ug/0.5mL) Injection, suspension Intramuscular A-S Medication Solutions 2006-06-08 Not applicable US Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU Gardasil Human papillomavirus type 6 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) Injection, suspension Intramuscular Merck Sharp & Dohme B.V. 2021-03-18 Not applicable EU
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 61746O90DY
- CAS number
- Not Available
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Active Not Recruiting Prevention Allogeneic Hematopoietic Stem Cell Transplantation Recipient / Hematopoietic and Lymphoid System Neoplasm 1 4 Active Not Recruiting Prevention Cervical Cancer / Precancerous Cervical Lesions 1 4 Active Not Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) / Human Papillomavirus (HPV) Infections 1 4 Active Not Recruiting Prevention HPV Vaccinations / Human Papilloma Virus (HPV) 1 4 Active Not Recruiting Prevention Human Immunodeficiency Virus (HIV) Infections / Human Papilloma Virus (HPV) / Human Papillomavirus (HPV) Vaccine 1 4 Active Not Recruiting Prevention Human Papilloma Virus (HPV) 1 4 Active Not Recruiting Prevention Human Papilloma Virus (HPV) / Vaccine Preventable Diseases 1 4 Active Not Recruiting Prevention Papilloma Viral Infection 1 4 Completed Health Services Research Cervical Intraepithelial Neoplasia (CIN) / HPV-Related Cervical Carcinoma 1 4 Completed Other Cervical Cancer / Hpv / Verruca (Warts) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, suspension Intramuscular Suspension Intramuscular Injection, suspension Intramuscular; Parenteral Injection, solution Intramuscular Injection, suspension Intramuscular 40 mcg Solution Intramuscular Injection Injection, suspension - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 01, 2015 20:03 / Updated at February 13, 2021 10:52