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Oxeladin

Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.

PRLX 93936

PRLX 93936 is selectively toxic to cancer cells.

Fibrinolysin

The ointment is marketed by Pfizer under the brand name Fibrolan in a variety of countries (e.g. Switzerland). It is currently not approved in the USA.

Apatorsen

Apatorsen is a second generation antisense drug which in preclinical experiments, inhibits production of Heat Shock Protein 27 (Hsp27) a cell survival protein found at elevated levels in many human cancers

QR-333

QR-333 is a concentrated and standardized nutrient based active compounds dosed in a topical cream designed to reduce oxidative stress and treat symptoms of Diabetic Peripheral Neuropathy, a nerve disorder … that can lead to numbness, skin ulcers, constant pain or extreme sensitivity to a stimulus.

Ticalopride

Fosinoprilat

Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.

YKP-1358

In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects. … YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia.

Latiglutenase

SB-509

SB-509 is under investigation in multiple clinical trials for the treatment of Diabetic Neuropathy.