YKP-1358

DB06109ExperimentalSmall molecule

YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia. In addition, the... In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.

Mechanism
Curator reviewed
Primary indication
Investigated for use/treatment in schizophrenia and schizoaffective disorders.Curator reviewed
Code names
YKP-1358

Resolves to

What you can answer from here — as of April 02, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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719Drug interactionsStructured to mechanism, not free text
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with YKP-1358, and which of those have an active Phase 3 trial?

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