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Displaying results 5251 - 5260 of 10000 in total
  1. Drug

    Saw palmetto

    go.drugbank.com/drugs/DB14360
    Approved

    Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  2. Drug

    Norclozapine

    go.drugbank.com/drugs/DB05766
    Investigational

    It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today. … ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia.

    Synonyms: N-Desmethylclozapine
  3. Drug

    DDP733

    go.drugbank.com/drugs/DB05049
    Investigational

    Serotonin is a neurotransmitter that is known to be involved in the control of the gastrointestinal (GI) system. … DDP733 is an oral prokinetic drug which Dynogen is developing as a treatment for both Irritable Bowel Syndrome with constipation (IBS-c) and nocturnal gastroesophageal reflux disease (NGERD).

  4. Drug

    Mizacorat

    go.drugbank.com/drugs/DB21458
    Investigational

    Mizacorat is under investigation in clinical trial NCT04556760 (Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared to Prednisolone, in Adults With Type 2 Diabetes … The usage of the INN stem '-corat' in the name indicates that Mizacorat is a glucocorticoid receptor agonist.

  5. Drug

    Olomorasib

    go.drugbank.com/drugs/DB21697
    Investigational

    Olomorasib is under investigation in clinical trial NCT06890598 (Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small … The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.

  6. Drug

    OM85

    go.drugbank.com/drugs/DB16533
    Investigational

    OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.

  7. Drug

    Idarucizumab

    go.drugbank.com/drugs/DB09264
    Approved

    Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations.

  8. Drug

    alpha-Amyl cinnamaldehyde

    go.drugbank.com/drugs/DB14175
    Approved

    It is used in allergenic testing.

  9. Drug

    RST-001

    go.drugbank.com/drugs/DB17843
    Investigational

    RST-001 is a non-replicating recombinant adeno-associated virus vector containing a fragment of the gene encoding channel rhodopsin-2 protein.

  10. Drug

    3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide

    go.drugbank.com/drugs/DB08092
    Experimental

    These are aromatic compounds containing a morpholine ring and a benzene ring linked to each other through a CC or a CN bond. This drug targets mitogen-activated protein kinase 14. … 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide is a solid. This compound belongs to the phenylmorpholines.

    Synonyms: 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide