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Displaying results 5251 - 5260 of 10000 in total
  1. Drug

    Ovatodiolide

    go.drugbank.com/drugs/DB19264
    Investigational

    Ovatodiolide is under investigation in clinical trial NCT04220411 (A Study for AR100DP1 in Mild to Moderate Atopic Dermatitis (AD)).

    Synonyms: (3as,6e,13s,15e,16ar)-3a,4,5,8,9,13,14,16a-octahydro-6,15-dimethyl-3-methylene-11h-13,10-methenofuro(2,3-f)oxacyclopentadecin-2,11(3h)-dione, 11h-13,10-methenofuro(2,3-f)oxacyclopentadecin-2,11(3h)-dione, 3a,4,5,8,9,13,14,16a-octahydro-6,15-dimethyl-3-methylene-, (3as,6e,13s,15e,16ar)-
  2. Drug

    Calanolide A

    go.drugbank.com/drugs/DB04886
    Investigational

    Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. … A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared with placebo.

    Synonyms: Calanolide A, (+)-calanolide A
  3. Drug

    Eritoran

    go.drugbank.com/drugs/DB04933
    Investigational

    Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.

  4. Drug

    CVT-6883

    go.drugbank.com/drugs/DB05936
    Experimental

    CVT-6883 is a selective, potent and orally available A2B-adenosine receptor antagonist which CV Therapeutics is investigating for the potential treatment of asthma and other conditions related to inflammation

  5. Drug

    Terevalefim

    go.drugbank.com/drugs/DB16397
    Investigational

    Terevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).

  6. Drug

    AN-9

    go.drugbank.com/drugs/DB05103
    Investigational

    than BA in preclinical studies. … Pivaloyloxymethyl butyrate (AN-9), an acyloxyalkyl ester prodrug of butyric acid (BA), exhibited low toxicity and significant anticancer activity in vitro and in vivo.

    Synonyms: AN-9
  7. Drug

    Xelaglifam

    go.drugbank.com/drugs/DB21598
    Investigational

    Xelaglifam is a small molecule drug. Xelaglifam is under investigation in clinical trial NCT04982705 (IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics). … Xelaglifam has a monoisotopic molecular weight of 501.2 Da.

  8. Drug

    Diethanolamine

    go.drugbank.com/drugs/DB20489
    Investigational

    Diethanolamine is a small molecule drug. Diethanolamine is under investigation in clinical trial NCT02499549 (Two Treatment Regimens of Cocamide DEA Lotion for Head Lice). … Diethanolamine has a monoisotopic molecular weight of 105.08 Da.

    Synonyms: N,n'-iminodiethanol
  9. Drug

    AGS-004

    go.drugbank.com/drugs/DB05742
    Investigational

    This approach may overcome the weaknesses of other available therapies and therefore could result in a better chance of success for HIV treatment. … A personalized immunotherapy addresses these issues because it is able to capture private viral mutations, providing a matched, complete immune response for each individual HIV patient.

  10. Drug

    Fosravuconazole

    go.drugbank.com/drugs/DB15204
    Investigational

    Fosravuconazole is under investigation in clinical trial NCT03378661 (BENDITA BEnznidazole New Doses Improved Treatment and Associations).

    Categories: Antifungals for Systemic Use, Antifungals for Dermatological Use