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PPI-2458
go.drugbank.com/drugs/DB05864InvestigationalThis class of compounds has been shown to prevent both abnormal cell growth and the formation of new blood vessels (known as angiogenesis), which contribute to the growth of aberrant tissues in diseases … In preclinical studies to date, PPI-2458 has demonstrated the potent pharmacologic activity of this class of compounds while displaying an improved pharmacokinetic and toxicity profile.
Recombinant alpha 1-antitrypsin
go.drugbank.com/drugs/DB05481InvestigationalrAAT belongs to a family of structurally-related proteins classified as serine protease inhibitors or SERPINS, which are known to inhibit several proteases including trypsin, cathepsin G, thrombin, tissue … Recombinant alpha 1-antitrypsin (rAAT) is produced from yeast, which unlike commercially available forms of plasma-derived AAT, eliminates the risk associated with blood-borne infectious agents and allows
Phencyclidine
go.drugbank.com/drugs/DB03575ExperimentalIllicitIt exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust. … Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state.
p-Fluorofentanyl
go.drugbank.com/drugs/DB09177ExperimentalIllicitthe introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as … p-Fluorofentanyl is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. p-Fluorofentanyl was sold briefly on the US black market in the early 1980s, before
QXL138AM
go.drugbank.com/drugs/DB18552InvestigationalQXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Synonyms: Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2aMe-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
Atabecestat
go.drugbank.com/drugs/DB15307InvestigationalAtabecestat is under investigation in clinical trial NCT02211079 (A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9,
Lumiliximab
go.drugbank.com/drugs/DB06162InvestigationalIt is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions.
Arachidonic Acid
go.drugbank.com/drugs/DB04557ApprovedInvestigationalWithdrawnIt is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. … It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem]
Mixtures: SIMILAC ALIMENTUM 400 G TOZFusafungine
go.drugbank.com/drugs/DB08965ApprovedWithdrawnFusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.