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Displaying results 5281 - 5290 of 10000 in total
  1. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … [L4779] It was also approved by the European Commission on January 7, 2021.[L45241]

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADET, XOFLUZA 40 MG FİLM KAPLI TABLET, 2 ADET
  2. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Synonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidMixtures: BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADET, BONEX-D 70 MG / 2800 IU TABLET, 4 ADET
  3. Drug

    Octreotide

    go.drugbank.com/drugs/DB00104
    ApprovedInvestigational

    Acromegaly is a life-threatening disease requiring life-long management. … Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SANDOSTATIN VIALES PARA DOSIS MULTIPLE 1 MG/ 5 ML, SANDOSTATIN LAR 20 MG ENJEKSİYONLUK SÜSPANSİYON İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET
  4. Drug

    Nusinersen

    go.drugbank.com/drugs/DB13161
    ApprovedInvestigational

    An antisense oligonucleotide that induces survival motor neuron (SMN) protein expression, it was approved by the U.S. FDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy (SMA). It is ad...

    Categories: Survival Motor Neuron-2-directed RNA InteractionProducts: SPİNRAZA 12 MG/5 ML INTRATEKAL ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, SPINRAZA ®12 MG SOLUCION INYECTABLE
  5. Drug

    Racementhol

    go.drugbank.com/drugs/DB14123
    ApprovedInvestigational

    Synonyms: (1R,2S,5R)-Menthol, p-Menthan-3-olMixtures: DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAK, Pranicura 5
  6. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    Due to its sufactant properties, P188 may also be found in over-the-counter (OTC) products such as toothpaste, laxatives and mouthwash, and used in various cosmetic, industrial and pharmaceutical applications … Composed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons.

    International brands: Lutrol FCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    A high-concentration, citrate-free formulation of Cyltezo® (adalimumab-adbm), a biosimilar to Humira®, was approved by the FDA in May 2024 for the treatment of multiple chronic inflammatory diseases. … A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818].

    Products: AMGEVITA 40 MG ILO I E PEN, HUMIRA 40MG ILO I E FER
  8. Drug

    Agalsidase beta

    go.drugbank.com/drugs/DB00103
    ApprovedInvestigational

    While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta. … Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa].

    Products: ฟาบราไซม์ (5 มก.), REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET
  9. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Still docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].

    Mixtures: Laxatif De Sene Et Docusate De Sodium, Sennosides 8.6 Mg and Docusate Sodium 50 Mg TabletsProducts: Sirop Docusate De Sodium U.S.P. 4mg/ml, H E B Stool Softener laxative
  10. Drug

    Goserelin

    go.drugbank.com/drugs/DB00014
    ApprovedInvestigational

    Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. … In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state.

    Products: ZOLADEX ® LA 10.8 MG, ZOLADEX ® 3.6MG