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LSZ-102
go.drugbank.com/drugs/DB15362InvestigationalLSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
RUTI® Vaccine
go.drugbank.com/drugs/DB15853InvestigationalMuch like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2. … Sponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488).
SR 140333
go.drugbank.com/drugs/DB05790ExperimentalSR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Tamuzimod
go.drugbank.com/drugs/DB21621InvestigationalTamuzimod has a monoisotopic molecular weight of 545.0 Da. … Tamuzimod is under investigation in clinical trial NCT05156125 (VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis).
Bimokalner
go.drugbank.com/drugs/DB21717InvestigationalBimokalner has a monoisotopic molecular weight of 355.1 Da. … Bimokalner is under investigation in clinical trial NCT06521190 (ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin).
BOS172722
go.drugbank.com/drugs/DB15498InvestigationalBOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. … The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects.
p-Fluorofentanyl
go.drugbank.com/drugs/DB09177ExperimentalIllicitanalogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. p-Fluorofentanyl was sold briefly on the US black market in the early 1980s, before the introduction of the Federal Analog Act which for … their structural similarity rather than scheduling each drug individually as they appeared. p-Fluorofentanyl is made with the same synthetic route as fentanyl, but by substituting para-fluoroaniline for
Tesaglitazar
go.drugbank.com/drugs/DB06536InvestigationalTesaglitazar is a proposed treatment for type 2 diabetes and has completed several phase III clinical trials, however in May 2006 AstraZeneca announced that they had discontinued further development. … Tesaglitazar is a dual peroxisome proliferator-activated receptor alpha/gamma agonist which improves apolipoprotein levels in non-diabetic subjects with insulin resistance.
GTI-2040
go.drugbank.com/drugs/DB15030ExperimentalGTI-2040 is under investigation in clinical trial NCT00084643 (GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors).
Veliflapon
go.drugbank.com/drugs/DB16346InvestigationalVeliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).