Search
Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. The extended-release forms of the drug are also available generically and under the brand name Imdur. … [T28] First approved by the FDA in 1991,[L11743] isosorbide mononitrate is used for the prevention and management of angina pectoris caused by coronary artery disease; however, the onset of action of
Synonyms: IS 5-MN, IS-5-MNCategories: Vasodilators Used in Cardiac DiseasesMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approvedMethocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. … [L6295] A combination product with [acetylsalicylic acid] and [codeine] is available in Canada by prescription.[L6295] Methocarbamol was FDA approved on 16 July 1957.[L6265]
Products: Robaxin Inj 100mg/ml, Robaximol Inj 100mg/mlTicarcillin
go.drugbank.com/drugs/DB01607ApprovedVet approvedWithdrawnAn antibiotic derived from penicillin similar to carbenicillin in action.
Products: Ticar Inj Pws 1gm/vial, Ticar Inj Pws 3gm/vialIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID. … In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194]
Mixtures: Doc in the Box All Day Supply, Combogesic IVProducts: Help I Have an Aching Body, CounterAct IBPhylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigational[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity … [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.
Mixtures: Mvc 9+4 Inj, CALCIDOSE 1200 MG/800 IU/65 MCG EFERVESAN TABLET, 45 ADETProducts: Vitamin K1 Inj 2mg/ml, Vitamin K1 Inj 10mg/mlCholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnNormally, it is an endogenous hormone but is available commercially for diagnostic processes and replacement in pancreatic insufficiency [L1646, L1647, L1648]. in the octapeptide form. … Recent studies have suggested that cholecystokinin also plays a major role in inducing drug tolerance to opioids such as morphine and heroin, and is partially implicated in experiences of pain hypersensitivity
Products: Cholecystokinin Inj 75unit/vialDesmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalIt is considered a first-line therapy for central diabetes insipidus but is ineffective in patients with nephrogenic diabetes insipidus, where the kidneys are non-responsive to the hormone [A275458, L56105 … Desmopressin is primarily indicated for the treatment of central diabetes insipidus, primary nocturnal enuresis (bedwetting) in children, and nocturia in adults [A275458, L56104].
Products: Ddavp Inj 4mcg/ml, Octostim Liq Inj. 15mcg/mlTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigational/in-clinic injection procedures that may inconvenience patients with frequent visits to the clinic [L4659]. … [A31615] This testosterone derivative was first approved on December 24, 1953.[L8941] In 2017, about 6.5 million retail prescriptions for testosterone therapy were filled [L4659].
Products: Testosterone Enanthate Inj 200mg/ml, PMS-testosterone Enanthate Inj 200mg/ml USPTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigationalIn 2004, topiramate was approved for the prevention of migraine in adults. … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996.
Products: Topamax 15 mg Granulat in Kapseln, Topamax 25 mg Granulat in KapselnPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B was discovered in the 1940s[A176429]. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes[A176426].
Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticProducts: POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 10 FLAKON, POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 1 FLAKON